Insights

Data Visualizations

View on desktop to access an interactive version of this timeline.

Early insights from our research illuminate the variety of pathways and timelines between milestones for a selection of the studied interventions.

Intervention:YearAntenatal corticosteroidsBiliChekChlorhexidineHIV self-testLong-lasting insecticide-treated netsMagnesium sulfatePre-exposure prophylaxis (PrEP)Sayana® PressTafenoquineUterine balloon tamponadeVitamin A supplementationXpert® MTB/RIF1924194719701975198019851990199520002005201020152020IdeationMilestone:Proof of conceptSRA approval1st in-country launchApproval by WHO body or other global procurement listWHO initial policy guidelinesWHO latest policy guidelinesCRITICAL MILESTONES OF VARIOUS HEALTH INTERVENTIONS:IDEATION TO FIRST LOW/MIDDLE-INCOME COUNTRY LAUNCH (1965-2020)Key TermsIdeation: Date of discovery or idea for specific interventionProof of Concept: Intervention demonstrated to be safe and effective for intended purpose in humansSRA: Stringent Regulatory Authority (Approval from a stringent regulatory body as defined by ICH)Source: Duke Global Health Innovation Center http://www.launchandscalefaster.org

Featured Publications

Scaling malaria interventions
Scaling malaria interventions: bottlenecks to malaria elimination

The slow progress in malaria control efforts and increasing challenges have prompted a need to accelerate the research and development (R&D), launch and scaling of effective interventions for malaria elimination. this research, including desk research and key informant interviews, identified the following challenges along the end-to-end scale-up pathway of malaria interventions.

Comparing research and development, launch, and scale up...
Comparing research and development, launch, and scale up timelines of 18 vaccines: lessons learnt from COVID-19 and implications for other infectious diseases

Over the next decade, millions of deaths could be prevented by increasing access to vaccines in low-income and middle-income countries (LMICs). The COVID-19 pandemic has demonstrated that the research and development (R&D), Launch and scale up timelines of vaccines can be drastically shortened.

User Guide
Measuring and Analyzing the Launch and Scale of Life Saving Health Interventions

This user guide is intended to support better measurement and understanding of the pathways and key factors involved in the launch and scale of health interventions in LMICs. 

A Framework for Measuring the Launch and Scale of Service Delivery...
A Framework for Measuring the Launch and Scale of Service Delivery Interventions in Low resource Settings

Low-and middle-income countries are increasingly faced with competing health challenges that may be addressed through health care interventions implemented by organizations operating outside of the public sector. Insufficient public sector care delivery infrastructure and limited workforce, combined with slow scaling of service delivery interventions implemented by social enterprises, NGOs, and the private sector, leads to global delivery gap in these settings.

Resources

Conducting research into the variety of interventions and their launch and scale pathways requires significant review of white and gray literature, reports, articles, and other materials. A sample of these resources that have informed our research are aggregated along the launch and scale framework dimensions.